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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK1
All Species:
38.48
Human Site:
T253
Identified Species:
70.56
UniProt:
Q96SB4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SB4
NP_003128.3
655
74325
T253
P
S
G
S
A
V
S
T
A
P
Q
P
K
P
A
Chimpanzee
Pan troglodytes
XP_518428
831
92792
T429
P
S
G
S
A
V
S
T
A
P
Q
P
K
P
A
Rhesus Macaque
Macaca mulatta
XP_001116721
831
92803
T429
P
S
G
S
A
V
S
T
A
P
Q
P
K
P
A
Dog
Lupus familis
XP_850330
823
92006
T421
P
S
G
S
A
V
S
T
A
P
Q
P
K
P
A
Cat
Felis silvestris
Mouse
Mus musculus
O70551
648
73070
T253
P
S
G
S
A
V
S
T
A
P
Q
P
K
P
A
Rat
Rattus norvegicus
NP_001020897
655
73837
T253
P
S
G
S
A
V
S
T
A
P
Q
P
K
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516210
528
59280
E196
P
P
S
D
M
A
F
E
K
L
D
K
K
I
P
Chicken
Gallus gallus
XP_419265
754
84415
T344
P
S
G
S
A
V
S
T
A
P
Q
P
K
P
A
Frog
Xenopus laevis
NP_001085122
605
68633
T253
P
S
G
S
A
V
S
T
A
P
P
P
K
Q
S
Zebra Danio
Brachydanio rerio
NP_001074138
640
71523
T250
P
S
G
S
A
V
S
T
A
P
A
P
K
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
S330
D
L
G
T
A
C
A
S
A
S
I
S
I
P
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
T95
F
E
L
G
D
D
L
T
P
R
Y
K
I
Y
S
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
S334
L
Q
R
H
V
S
R
S
S
D
I
T
A
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
78.2
76.7
N.A.
91.4
91.4
N.A.
65.5
70.1
67.6
64.7
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
100
78.6
78.5
77.6
N.A.
94.6
94
N.A.
70.3
77.3
78.1
76.1
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
80
86.6
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
86.6
86.6
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
77
8
8
0
77
0
8
0
8
0
62
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
8
8
0
0
0
8
8
0
0
0
8
% D
% Glu:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
77
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
16
0
16
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
16
77
0
0
% K
% Leu:
8
8
8
0
0
0
8
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
77
8
0
0
0
0
0
0
8
70
8
70
0
62
8
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
54
0
0
16
0
% Q
% Arg:
0
0
8
0
0
0
8
0
0
8
0
0
0
0
8
% R
% Ser:
0
70
8
70
0
8
70
16
8
8
0
8
0
0
16
% S
% Thr:
0
0
0
8
0
0
0
77
0
0
0
8
0
0
0
% T
% Val:
0
0
0
0
8
70
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _